If you find that the Settings app in Windows 10 does not launch or open, or it launches the Store app instead, then this Troubleshooter from Microsoft will fix the problem for you.

Windows 10 Settings app does not open

Microsoft is aware of this issue. Some Windows 10 users have reported that after they installed or upgraded to Windows 10, when the click to open the settings app, if just does not open. Yet others have reported that it opens the Store app instead.

Microsoft has classified this as Emerging Issue 67758, and till such a time that a solution is found, has released this troubleshooter, which you can safely use to fix the problem.

Once you have downloaded it, click on the file to run it. Once it opens, click on Next.

It will take you to a screen which will say Fix or work around emerging issue 67758. Click Next again.

The tool will scan your system and identify if this applies to your system and if any issues are found, it will report so, and will offer to fix them.

If none are found, it will report, Issue not present.

Download the troubleshooter from Microsoft.

Let us know if this worked for you.

Thanks for the tip Andy Malone.

Workaround: Create a new local administrator account as follows. Add it through the Control Panel or Run or search for lusrmgr.msc and open the Microsoft Common Console Document.  Select and right click ‘Users’, choose ‘Add new user’ to do the needful. Now using Ctrl+Alt+Del, sign out of your account and then sign in to your newly created account.  If you can now open Settings, move your personal data and files to the new account and make the new account an Administrator account:

UPDATE: Microsoft has  released Cumulative Update for Windows 10 KB3081424 includes a fix that will prevent this issue from occurring,